Isha received her undergraduate degree in Chemical and Physical Biology from Harvard University. There, she worked in the lab of Erin O’Shea on bacterial chromosome segregation. Subsequently, she joined the Harvard-MIT Program in Health Sciences and Technology. During her PhD, she worked in the labs of Vamsi Mootha and Warren Zapol, where she discovered that hypoxia could serve as a therapy for mitochondrial disorders. This work led to a Phase 1 clinical trial. Isha began as a UCSF Sandler Faculty Fellow and then became an Assistant Professor at the Gladstone Institutes and UCSF in 2021. She has received the NIH Early Independence Grant, Searle Scholar Award, Klingenstein-Simons Award, Mallinckrodt Award, TRDRP New Investigator Award, AFAR Junior Faculty Award, Hillblom Start-Up Grant, and Keck Medical Research Grant.

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