【代表性论文】(#第一作者,*通讯作者)1.Wang B#, Jie ZL#, Joo D, Ordureau A, Liu PD, Gan WJ, Guo JP, Zhang JF, North B, Dai XP, Cheng XH, Bian XW, Zhang LQ, Harper JW, Sun SC*, Wei WY*. TRAF2 and OTUD7B govern a ubiquitin-dependent switch that regulates mTORC2 signalling.Nature. 2017;545:365-369.2. Qin ZY#, Wang T#, Su SY , Shen LT, Zhu GX, Liu Q, Zhang L, Liu KE, Zhang Y, Zhou ZH, Zhang XN, Wen LZ, Yao YL, Sun WJ, Guo Y, Liu KJ, Liu L, Wang XW, Wei YL, Wang J, Xiao HL, Liu PD, Bian XW, Chen DF*,Wang B*. BRD4 promotes gastric cancer progression and metastasis through acetylation-dependent stabilization of Snail.Cancer Res. 2019;79(19):4869-4881.3. Wang T#, Qin ZY#, Wen LZ#, Guo Y, Liu Q, Lei ZJ, Pan W, Liu KJ, Wang XW, Lai SJ, Sun WJ, Wei YL, Liu L, Guo L, Chen YQ, Wang J, Xiao HL, Bian XW, Chen DF*,Wang B*. Epigenetic restriction of Hippo signaling by MORC2 underlies stemness of hepatocellular carcinoma cells.Cell Death Differ. 2018;25:2086-2100.4. Lei ZJ, Wang J, Xiao HL, Guo Y, Wang T, Li Q, Liu L, Luo X, Fan LL, Lin L, Mao CY, Wang SN, Wei YL, Lan CH , Jiang J, Yang XJ, Liu PD, Chen DF, andWang B* Lysine-specific demethylase 1 promotes the stemness and chemoresistance of Lgr5+liver cancer initiating cells by suppressing negative regulators of β-catenin signaling.Oncogene.2015; 34:3188-98. (Featured Article)5.Wang B #, Wang Q#, Wang Z#, Jiang J, Yu SC, Ping YF, Yang J, Xu SL, Ye XZ, Xu C, Yang L, Qian C, Wang JM, Cui YH, Zhang X, Bian XW*. Metastatic consequences of immune escape from NK cell cytotoxicity by human breast cancer stem cells.Cancer Res. 2014;74:5746-57. 6. Wang Z#, Wang B#, Shi Y#, Xu C, Xiao HL, Ma LN, Xu SL, Yang L, Wang QL, Dang WQ, Yu SC, Ping YF, Cui YH, Kung HF, Qian C, Zhang X, Bian XW*. Oncogenic miR-20a and miR-106a enhance the invasiveness of human glioma stem cells by directly targeting TIMP-2.Oncogene. 2015;34: 1407-1419.7. Wang T#, Wu H#, Liu S#, Lei ZJ#, Qin ZY, Wen LZ, Guo Y, Liu Q, Liu L, Wang J, Lin L, Mao CY, Zhu XF, Xiao HL, Bian XW, Chen DF*, XuC*,Wang B*. SMYD3 controls a Wnt-responsive epigenetic switch for ASCL2 activation and cancer stem cell maintenance.Cancer Lett. 2018. 430:11-24.8. Wang J, Lei ZJ, Guo Y, Wang T, Qi ZY, Xiao HL, Fan LL, Chen DF, Bian XW, Liu J, andWang B*. miRNA-regulated delivery of lincRNA-p21 suppresses β-catenin signaling and tumorigenicity of colorectal cancer stem cells.Oncotarget. 2015; 6:37852-70.9.Wang B, Liu J, Ma L, Xiao H, Wang Y, Li Y, Wang Z, Fan L, Lan C, Yang M, Hu L, Wei Y, Bian X, Chen D, Wang J*. Chimeric5/35 adenovirus-mediated dickkopf-1 overexpression suppressed tumorigenicity of CD44+gastric cancer cells via attenuating Wnt signaling.J Gastroenterol 2013;48:798-808.10. Wang J#, Wang B#, Chen DF. A rare submucosal tumor of the stomach.Gastroenterology. 2013; 144:e5-6.11. Wang J#, Wang B#, Chen DF.An unusual cause of recurrent massive upper gastrointestinal bleeding.Gastroenterology. 2012; 143:542, 872.12. Qin ZY, Xiao X*,Wang B*.Recurrent Hematochezia and Hemoptysis due to Colon-Pulmonary Fistula.Am J Gastroenterol. 2019; doi: 10.14309. [Epub ahead of print].13.Wang B, Yu SC, Jiang JY, Porter GW, Zhao LT, Wang Z, Tan H, Cui YH, Qian C, Ping YF, Bian XW*. An inhibitor of arachidonate 5-lipoxygenase, Nordy, induces differentiation and inhibits self-renewal of glioma stem-like cells.Stem Cell Rev 2011; 7:458-70.