编辑：胡则辉时间：2024-04-23访问次数：0
李建峰，副教授，主持国家自然科学基金2项、浙江省自然科学基金2项。入选杭州市高层次人才E类，杭州市131人才第三层次，杭州师范大学卓越人才第五层次。
教育背景
1. 2003年9月--2007年6月，浙江师范大学，理学学士
2. 2007年9月--2009年6月，南京师范大学，理学硕士
主要工作简历
2013年1月—至今，杭州师范大学基础医学院，讲师、副教授
主持科研项目
1. 浙江省自然科学基金青年项目，抗菌肽 CMⅣ 的修饰改造及抗绿脓杆菌的作用研究，5万元，2013/01-2015/12。
2. 浙江省自然科学基金一般项目，PD模型小鼠脑内金属离子紊乱与α-突触核蛋白异常聚集的相关性研究，2021/01-2023/12。
3. 国家自然科学基金青年项目，ATP13A2 调控锰离子依赖性 α-synuclein 寡聚体形成作用的研究，22.8万元，2016.01–2018.12。
4. 国家自然科学基金面上项目，鞘脂运转紊乱与 α-synuclein 相变在帕金森氏病发生发展中的作用，55万元，2020/01-2023/12。
代表性论著(* corresponding author)
1. Liu MY, Tao MX, Li JF (co-first author), Sang M, Wu XL, Luo HB, Zhang JX*. Functional of tongue sole (Cynoglossus semilaevis) gamma-interferon-inducible lysosomal thiol reductase with implications in innate immune reponse depend on CXXC active site. Dev Comp Immunol. 2023 Oct;147:104901
2. Li JF*, Zhang JX, Li G, Xu YY, Lu K, Wang ZG*, Liu JP*. Antimicrobial activity and mechanism of peptide CM4 against Pseudomonas aeruginosa. Food Funct. 2020 Aug 19;11(8):7245-7254.
3. Wang Z, Li JF*, Liu JP*. Effects of cation charges on the binding of stabilizers with human telomere and TERRA G-quadruplexes. J Biomol Struct Dyn. 2018.5; 28:1-14.
4. Jian Feng Li*, Jia Xin Zhang, Zhi Guo Wang, Ying Jia Yao, Xu Han, You Long Zhao, Jun Ping Liu*, Shuang Quan Zhang*, Identification of a cyclodextrin inclusion complex of antimicrobial peptide CM4 and its antimicrobial activity, Food Chemistry, 2017.
5. Liu H, Zhang J, Jian Feng Li (co-first author), Song J, Zhang S, Molecular structure, distribution, and immunology function of TNFSF13B (BAFF) in Nile tilapia (Oreochromis niloticus). Fish & Shellfish Immunology, 2016, 51, 240-250.
6. Jian Feng Li, Wang ZG, Liu HZ, Zhao YL, Zhang JX, Zhang SQ, Liu JP， Identification of interferon-γ-inducible-lysosomal thiol reductase (GILT) gene in goldfish (Carassius auratus) and its immune response to LPS challenge，Fish & Shellfish Immunology，2015，42，465-472.
7. Zhang J, Jian Feng Li (co-first author), Movahedi A, Sang M, Xu C, Xu J, Wei Z, Yin T, Zhuge Q, A novel inclusion complex (β-CD/ABP-dHC-cecropin A) with antibiotic propertiess for use as an anti-Agrobacterium additive in transgenic poplar rooting medium. Enzyme Microb Technol，2015，81：72–79.
8. Jian Feng Li, Jie Zhang, Ren Song, Jia Xin Zhang, Yang Shen and Shuang Quan Zhang*，Production of a cytotoxic cationic antibacterial peptide in Escherichia coli using SUMO fusion partner，Appl Microbiol Biot，84(2)，383-388，2009
9. Jian Feng Li, Jie Zhang, Zhen Zhang, Hong Wei Ma, Jia Xin Zhang and Shuang Quan Zhang*，Production of Bioactive Human Beta-Defensin-4 in Escherichia coli Using SUMO Fusion Partner，Protein J，29(5)，314-319，2010
10. Jian Feng Li, Jie Zhang, Zhen Zhang, Chun Tao Kang and Shuang Quan Zhang*，SUMO Mediating Fusion Expression of Antimicrobial Peptide CM4 from two Joined Genes in Escherichia coli，Curr Microbiol，62(1)，296-300，2010
11. Jian Feng Li, Hong Xing Ai, Jie Zhang, Ming Xiang Du, Zhen Zhang, Jia Xin Zhang and Shuang Quan Zhang*，Molecular cloning, functional characterization and phylogenetic analysis of Trail in Japanese pufferfish Takifugu rubripes，J Fish Biol，79，747-760，2011
12. Jian Feng Li, Jie Zhang, Xing Zhou Xu, Yang Yang Han, Xian Wei Cui, Yu Qing Chen, Shuang Quan Zhang*，The antibacterial peptide ABP-CM4: the current state of its production and applications. Amino Acids，42，2393-2402，2012
13. Jian Feng Li, XianWei Cui, HaiYan Ji, Ting Qiu, Xue Mei Ji, Ming Xian Du, Hai Tao Wu, Xing Zhou Xu, Shuang Quan Zhang*，High efficient expression of bioactive human BMP-14 in E.coli using SUMO fusion partner，Protein J，30，592–597，2011