导航菜单

潘昕

联系方式

办公电话:020-39943427

电子邮箱:panxin2@mail.sysu.edu.cn    

办公地址:广州市大学城外环东路132号中山大学药学院214A室

简单介绍

潘昕,中山大学药学院教授,博导,教育部长江学者奖励计划青年学者、广东省杰出青年、珠江科技新星人才。2011年毕业于中山大学,获药剂学博士学位,后留校任教,美国The University of Texas at Austin访问学者。主要研究方向为药物新剂型和新技术。以单独通讯/共同通讯作者身份,在J Control Release, ACS Nano, Acta Pharm Sin B等发表论文发表SCI论文60余篇,获得授权专利27项,其中12项专利已实现有偿转化。作为主要完成人,荣获2019中国产学研合作创新成果一等奖(2/10)、2020中国发明创业创新奖二等奖(2/6)、2018广东省科学技术奖二等奖(3/10)、2016 年中国产学研合作创新成果二等奖(3/7)等奖项,个人获中国药物制剂大会青年药剂学奖。10余次应邀在国际国内作学术报告,包括第十六届中国药物制剂大会(中国长沙,2022)、Particulate Processes in the Pharmaceutical Industry IV(Potsdam, Germany, 2016)等。主持科研项目十余项,包括国家自然科学基金面上项目(3项)、广东省自然科学基金杰出青年项目、“十三五”国家重大新药创制专项子课题、国家863计划子课题、广东省重点领域研发计划子课题及广东省团队项目等。指导的学生曾获全国专业硕士优秀论文奖、中山大学优秀博士论文奖、中国博士后创新人才计划等。学术兼职包括中国药学会药物制剂专业委员会青年委员、广东省药学会药物制剂委员会秘书长、《Pharmaceutics》编委、《Asian Journal of Pharmaceutical Science》青年编委、《Chinese Chemical Letters》青年编委、《药学进展》青年编委等。

研究方向

微针经皮药物递送系统;肺部药物递送系统

教育经历

2006.09-2011.06     博士,药剂学, 中山大学,广州 

2002.09-2006.07     学士,药学,中山大学,广州

工作经历

2024.4至今                  中山大学药学院    教授

2017-2018                  美国德克萨斯奥斯汀分校药学院  访问学者

2015-2024.4              中山大学药学院    副教授

2013.07-2015.12        中山大学药学院   讲师

2011.07-2013.06        中山大学药学院    师资博士后

社会/学术任职

1. 《Pharmaceutics》编委

2. 《Asian Journal of Pharmaceutical Science》青年编委

3. 《Chinese Chemical Letters》青年编委

4. 《药学进展》青年编委

5. 中国药学会药物制剂专业委员会 青年委员

6. 广东省药学会药物制剂委员会 秘书长

7. 广州市市场监督管理局食品药品特种设备安全专家委员会 委员

8. 广州市纳米生物医药科技促进会 理事

9. 第二届工业药学与临床药学研讨会组委会 组长

10. 美国药学科学家协会中山大学学生分会 (AAPS Sun Yat-Sen University Student Branch )  发起人

荣誉奖励

1. 中国产学研合作创新成果一等奖(第二完成人)

2. 中国发明创业创新奖二等奖(第二完成人)

3. 广东省科学技术奖二等奖(第三完成人)

4. 中国药物制剂大会青年药剂学奖

5. 《Acta Pharm Sin B》杰出论文奖

6. 广州市“珠江科技新星”

科研项目活性氧气微泡驱动微针递药系统用于瘢痕疙瘩的高效治疗机制研究,国家自然科学面上项目,49万元,项目负责人,项目编号:82373803,2024/01-2027/12。可控晶格的动态智能液晶系统用于软组织缺损修复及其机制研究,国家自然科学面上项目,55万元,项目负责人,项目编号:81973263,2020/01-2023/12。抗肿瘤新型纳米微针药物制剂关键技术及产业化研究,广东省重点领域研发计划,210/700万元,子课题负责人,项目编号:2019B020204002,2019/10-2022/12。“长效缓控释微球产业化共性关键技术与创新制剂研发-注射用促红细胞生成素微球,国家重大新药创制专项子课题,264.90万元,项目负责人,项目编号:2017ZX09201004-017,2017/01-2020/12。“干粉吸入剂二元载体表面微结构的定向构建及其增效机理的研究”,国家自然基金面上项目,51万,项目负责人,2017/01-2020/12。“药食同源多组分功能因子在临床营养制剂中的稳定性研究、工艺研究及中试、产品质量评价”,国家高技术研究发展计划(863 计划)子课题,90万元,项目负责人,项目编号:2014AA022204, 2014/01-2016/12。“基于超细微粒制备技术的微粒成丸机理研究及其在微丸片中的应用”,国家自然科学基金青年基金,23万元,项目负责人,项目编号:81202476,2013/01-2015/12。“超细微粒制造系统制备骨架微丸的机理研究及其在口崩微丸片产业化中的应用”,广州市珠江科技新星,30万元,项目负责人,项目编号:1317000297,2014/04-2017/03。“智能型低温超微粒药物制备系统的设计及理论研究”,广东省自然科学基金团队项目,50/300万元,核心成员等同于子课题负责人,项目编号:2016A030312013,2016/01-2018/12。“基于超细微粒制备技术的微粒成球机理研究及其在石杉碱甲口崩型缓释微丸片中的应用”,教育部博士点基金新教师类,4万元,项目负责人,项目编号:20120171120046,2012/01-2014/12。“基于超细微粒制备技术的微粒成丸机理及其在口崩型缓释微丸片的中的应用”,中国博士后科学基金委,5万元,项目负责人,项目编号:2012M511625,2011/01-2013/12。“石杉碱甲口崩型缓释微丸片的研究”,广东省卫生厅医学科研基金,0.5万元,项目负责人,项目编号:B2012079,2012/07-2014/06。“多孔/微粗糙甘露醇载体的形成机制及其在干粉吸入剂中的应用”,高校基本科研业务费中山大学青年教师培育项目,15万元,项目负责人,项目编号:16ykpy23,2016/01-2018/12。

论著专利部分代表性论文(近三年):D Yang#, M Chen#, Y Sun, C Shi, W Wang, W Zhao, T Wen, T Liu, J Fu, C Lu, C Wu, G Quan*, X Pan*. Microneedle-assisted vaccination combined with autophagy regulation for antitumor immunotherapy. J Control Release, 2023, 357: 641-654.W Wang#, F Fu#, Z Huang, W Wang, M Chen, X Yue, J Fu, X Feng, Y Huang, C Wu, X Pan*. Inhalable biomimetic protein corona-Mediated nanoreactor for self-amplified lung adenocarcinoma ferroptosis therapy,ACS Nano, 2022, 16:8370.W Wang#, Z Huang#, Y Huang, X Zhang, J Huang, Y Cui, X Yue, C Ma, F Fu, W Wang, C Wu, X Pan*. Pulmonary delivery nanomedicines towards circumventing physiological barriers Strategies and characterization approaches,Advanced Drug Delivery Reviews, 2022, 185, 114309:1-28.X Zhang, Y Cui, R Liang, G Wang, X Yue, Z Zhao, Z Huang,Y Huang, J. Geng, X Pan*, C Wu. Novel approach for real-time monitoring of carrier based DPIs delivery process via pulmonary route based on modular modified Sympatec HELOS,Acta Pharmaceutica Sinica B, 2020, 10,7:1331-1346.X Feng#, D Xian#, J Fu, R Luo, W Wang, Y Zheng, Q He, Z Ouyang, S Fang, W Zhang, D Liu, S Tang, G Quan, J Cai, C Wu, C Lu*, X Pan*. Four-armed host-defense peptidomimetics-augmented vanadium carbide MXene-based microneedle array for efficient photo-excited bacteria-killing. Chemical Engineering Journal, 2023, 456(15): 141121. T Peng, Y Chen, W Hu, Y Huang, M Zhang, C Lu*, X Pan*, C Wu*. Microneedles for Enhanced Topical Treatment of Skin Disorders: Applications, Challenges, and Prospects. Engineering. 2023, In press. J Fu, Y Zhou, T Liu, W Wang, Y Zhao, Y Sun, Y Zhang, W Qin, Z Chen, C Lu, G Quan, C Wu, X Pan*. A triple-enhanced chemodynamic approach based on glucosepowered hybrid nanoreactors for effective bacteria killing. Nano Research, 2023, In press.X Gao#, F Zhang#, Y Huang, W Hu, Y Chen, L Jiang, X Pan, C Wu*, C Lu*, T Peng*. Site-specifically launched microneedles for the combined treatment of psoriasis-diabetic comorbidity. ACS Appl Mater Inter, 2023, 15(40):46613-46625Y Huang, T Peng*, Y Chen, F Zhang, W Hu, X Gao, H Chen, P Tang, C Wu, X Pan*. An oxygen reservoir-irrigated photoimmunotherapy of malignant melanoma. Nano Res, 2023, 16:2875-2884Y Huang#, Z Chang#, X Xia#, Z Zhao, X Zhang*, Z Huang*, C. Wu, X. Pan*. Current and evolving knowledge domains of cubosome studies in the new millennium. J Nanopart Res. 2023; 25: 176M Guo, T Peng*, C Wu, X Pan, Z Huang*. Engineering ferroptosis inhibitors as inhalable nanomedicines for the highly efficient treatment of idiopathic pulmonary fibrosis. Bioengineering. 2023; 10(6): 727.Z Chang#, W Wang#, Z Huang*, Y Huang, C Wu, X Pan*. Lecithin reverse micelle is promising in constructing carrier particles for protein drugs encapsulated pressurized metered-dose inhalers. Adv Therapeut. 2023; Accepted Manuscript.W Wang#, J Zeng#, P Luo#, J Fang, Q Pei, J Yan, C Zhu, W Chen, Y Liu, Z Huang*, Y Huang*, C Wu, X Pan*. Engineered lipid liquid crystalline nanoparticles as an inhaled nanoplatform for mucus penetration enhancement. Drug Deliv Transl Re. 2023; Accepted Manuscript.W Wang#, W Wang#, S Jin, F Fu, Z Huang*, Y Huang*, C Wu, X Pan*. Open pocket and tighten holes: Inhalable lung cancer-targeted nanocomposite for enhanced ferroptosis-apoptosis synergetic therapy. Chem Eng J. 2023; 458: 141487.Y Sun#, M Chen#, D Yang, W Qin, G Quan*, C Wu, X Pan*. Self-assembly nanomicelle-microneedle patches with enhanced tumor penetration for superior chemo-photothermal therapy. Nano Research, 2022, 15: 2335-2346.B Niu#, Y Zhou#, K Liao, T Wen, S Lao, G Quan*, X Pan*, C Wu*. “Pincer movement”: reversing cisplatin resistance based on simultaneous glutathione depletion and glutathione s-transferases inhibition by redox-responsive degradable organosilica hybrid nanoparticles. Acta Pharm Sin B, 2022, 12(4): 2074-2088.J Fu, T Liu, X Feng, Y Zhou, M Chen, W Wang, Y Zhao, C Lu, G Quan, J Cai, X Pan*, C Wu. A perfect pair: stabilized black phosphorous nanosheets engineering with antimicrobial peptides for robust multidrug resistant bacteria eradication. Adv Healthcare Mater, 2022, 2101846.B Niu, K Liao, Y Zhou, T Wen, G Quan*, C Wu, X Pan*. Cellular defense system-destroying nanoparticles as a platform for enhanced chemotherapy against drug-resistant cancer. Materials Science and Engineering: C, 2021, 131, 112494. Y Zhou#, B Niu#, Y Zhao, J Fu, T Wen, K Liao, G Quan, X Pan*, C Wu*. Multifunctional nanoreactors-integrated microneedles for cascade reaction-enhanced cancer therapy. J Controll Release, 2021, 339: 335-349.B Niu, K Liao, Y Zhou, T Wen, G Quan, X Pan*, C Wu*. Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy. Biomaterials, 2021, 277: 121110. T Wen, Z Lin, Y Zhao, Y Zhou, B Niu, C Shi, C Lu, Xi Wen, M Zhang, G Quan,* C Wu, X Pan*. Bioresponsive nanoarchitectonics-integrated microneedles for amplified chemo-photodynamic therapy against acne vulgaris. ACS Appl. Mater. Interfaces, 2021, 13, 41, 48433-48448. Y Zhao#, Y Zhou#, D Yang, X Gao, T Wen, J Fu, X Wen, G Quan*, X Pan*, C Wu. Intelligent and spatiotemporal drug release based on multifunctional nanoparticle-integrated dissolving microneedle system for synergetic chemo-photothermal therapy to eradicate melanoma. Acta Biomaterialia, 2021, 2021, 135: 164-178.S Luo, Y Zhao, K Pan, Y Zhou, X Wen, G Quan*, X Wen, X Pan*, C Wu. Microneedle-mediated delivery of MIL-100(Fe) as a tumor microenvironment-responsive biodegradable nanoplatform for O2 evolving chemophototherapy. Biomater Sci, 2021, 9, 6772-6786.P Yang, M Chen, W Qin, C Shi, X Bai, G Quan*, X Pan*, C Wu. Effective photothermal therapy mediated by indocyanine green nanoparticle tip-loaded microneedles to enhance checkpoint inhibitors immunotherapy of melanoma. ACS Applied Nano Materials, 2021, 4(6): 5921-5931.M Chen#, D Yang#, Y Sun#, T Liu, W Wang, J Fu, Q Wang, X Bai, G Quan*, X Pan*, C Wu*. In situ self-assembly nanomicelle microneedles for enhanced photoimmunotherapy via autophagy regulation strategy. ACS Nano, 2021, 15, 2, 3387-3401.B Yang, Y Dong, Y Shen, A Hou, G Quan*, X Pan*, Bilayer dissolving microneedle array containing 5-fluorouracil and triamcinolone with biphasic release profile for hypertrophic scar therapy, Bioactive Materials, 2021, 6,8:2400-2411.T Wen#, G Quan#, B Niu, Y Zhou, Y Zhao, C Lu, X Pan*, C Wu*. Versatile nanoscale metal-organic frameworks (nMOFs): an emerging 3D nanoplatform for drug delivery and therapeutic applications. Small, 2021, 17(8): 2005064Y Shi, X Feng, L Lin, J Wang, J Chi, B Wu, G Zhou, F Yu, Q Xu, D Liu, G Quan, C Lu*, X Pan*, J Cai*, C Wu*. Virus-inspired surface-nanoengineered antimicrobial liposome: A potential system to simultaneously achieve high activity and selectivity. Bioactive Materials, 2021, 6(10): 3207-3217. T Peng, Y Huang, X Feng, C Zhu, Y Shi, X Wang, X Bai, X Pan*, C Wu*. TPGS/hyaluronic acid dual functionalized PLGA nanoparticles delivered through dissolving microneedles for markedly improved chemophotothermal combined therapy of superficial tumor. Acta Pharm Sin B, 2021, 11(10):3297-3309、S Wei, G Quan*, C Lu, X Pan*, C Wu. Dissolving microneedles integrated with pH-responsive micelles containing aiegen with ultra-photostability for enhancing melanoma photothermal therapy. Biomater Sci, 2020, 8(20): 5739-5750.B Wu, J Fu, Y Zhou, S Luo, Y Zhao, G Quan*, X Pan*, C Wu. Tailored core-shell dual metal-organic frameworks as a versatile nanomotor for effective synergistic antitumor therapy. Acta Pharm Sin B, 2020, 10(11): 2198-2211.W Qin#, G Quan#, Y Sun, M Chen, P Yang, D Feng, T Wen, X Hu, X Pan*, C Wu. Dissolving microneedles with spatiotemporally controlled pulsatile release nanosystem for synergistic chemo-photothermal therapy of melanoma. Theranostics, 2020, 10(18): 8179-8196.M Chen#, G Quan#, Y Sun, D Yang, X Pan*, C Wu*. Nanoparticles-encapsulated polymeric microneedles for transdermal drug delivery. J Control Release, 2020, 325: 163-175.M Chen#, G Quan#, T Wen, P Yang, W Qin, H Mai, Y Sun, C Lu, X Pan*, C Wu*. Cold to hot: binary cooperative microneedle array-amplified photoimmunotherapy for eliciting antitumor immunity and the abscopal effect. ACS Appl Mater Inter, 2020, 12(29): 32259-32269Z Huang, Y Huang, W Wang, F Fu, W Wang, S Dang, C Li, C Ma, X Zhang, Z Zhao, X Pan*, C Wu. Relationship between particle size and lung retention time of intact solid lipid nanoparticle suspensions after pulmonary delivery. J Control Release. 2020; 325: 206-222.W Wang#, Z Huang#, K Xue, J Li, W Wang, J Ma, C Ma, X Bai, Y Huang*, X Pan**, C Wu. Development of aggregation-caused quenching probe-loaded pressurized metered-dose inhalers with fluorescence tracking potentials. AAPS Pharmscitech. 2020; 21:296.Z Huang#, C Ma#, M Wu#, X Li, C Lu, X Zhang, X Ma, Y Yang, Y Huang*, X Pan**, C Wu. Exploring the drug-lipid interaction of weak-hydrophobic drug loaded solid lipid nanoparticles by isothermal titration calorimetry. J Nanopart Res. 2020; 22(3): 1-14.T Peng#, Y Huang#, X Feng, C Zhu, X Ma, X Wang, X Bai, X Pan*, C Wu*. Dissolving microneedles loading TPGS biphasic functionalized PLGA nanoparticles for efficient chemo-photothermal combined therapy of melanoma. Adv Therap 2020, 3:1900190 J Wang#, C Lu #, Y Shi, X Feng, B Wu, G Zhou, G Quan, X Pan,* J Cai,* and C Wu.* Structural Superiority of Guanidinium-Rich Four-Armed Copolypeptides: Role of Multiple Peptide-Membrane Interactions in Enhancing Bacterial Membrane Perturbation and Permeability. ACS Applied Materials & Interfaces. 2020, 12, 18363-18374. M Sun#, C Zhu#, J Long, C Lu*, X Pan* and C Wu. PLGA microsphere-based composite hydrogel for dual delivery of ciprofloxacin and ginsenoside Rh2 to treat Staphylococcus aureus-induced skin infections. Drug Delivery, 2020, 27(1): 632-641. B Wu, J Fu, Y Zhou, Y Shi, J Wang, X Feng, Y Zhao, G Zhou, C Lu*, G Quan*, X Pan, C Wu. Metal–organic framework-based chemo-photothermal combinational system for precise, rapid and efficient antibacterial therapeutics. Pharmaceutics 2019, 11, 463.Y Zhou#, Q Fang#, B Niu, B Wu, Y Zhao, G Quan*, X Pan*, C Wu. Comparative studies on amphotericin B nanosuspensions prepared by a high pressure homogenization method and an antisolvent precipitation method. Colloid Surface B. 2018, 172:372-379.B Niu, Y Zhou, T Wen, G Quan*, V Singh, X Pan*, C Wu. Proper functional modification and optimized adsorption conditions improved the DNA loading capacity of mesoporous silica nanoparticles, Colloid Surface A. 2018, 548:98-107. Y Zhou#, G Quan#, QWu, X Zhang, B Niu, B Wu, Y Huang, X Pan*, C Wu*. Mesoporous silica nanoparticles for drug and gene delivery. Acta Pharm Sin B. 2018, 8(2):165-177.Z Huang, H Wu, C Zhu, Y Huang, X Pan, C Wu*. Salmon calcitonin containing pressurized metered-dose inhaler based on anhydrous reverse micelle nanoparticles. Nanomed-Nanotechnol. 2018; 14: 1831.Z Huang, Y Huang*, C Ma, X Ma, X Zhang, L Lin, Z Zhao, X Pan**, C Wu. Endotracheal aerosolization device for laboratory investigation of pulmonary delivery of nanoparticle suspensions: In vitro and in vivo validation. Mol Pharmaceut. 2018; 15: 5521-5533.Z Huang#, H. Wu#, B Yang, L Chen, Y Huang, G Quan, C Zhu, X Li, X Pan*, C Wu. Anhydrous reverse micelle nanoparticles: New strategy to overcome sedimentation instability of peptide-containing pressurized metered-dose inhalers. Drug Deliv. 2017; 24(1): 527-538.Y Dong, P Dong, D Huang, L Mei, Y Xia, Z Wang, X Pan*, G Li, C Wu*, Fabrication and characterization of silk fibroin-coated liposomes for ocular drug delivery, Eur J Pharm Biopharm, 2015,91:82-90. G Quan, Xi Pan, Z Wang, Q Wu, G Li, L Dian, B Chen*, C Wu*, Lactosaminated mesoporous silica nanoparticles for asialoglycoprotein receptor targeted anticancer drug delivery, J Nanobiotech, 2015,13:7-18.Y Huang, C Zhu, G Li, X Pan*, C Wu. Metoprolol tartrate sustained-release binary matrix microspheres for oral administration produced by novel ultra-fine particle processing system, Powder Technol, 2015, 285: 44-50.C Zhu, Y Huang, X Zhang, L Mei, G Li, X Pan*, C Wu *, Comparative studies on exenatide-loaded poly (D, L-lactic-co-glycolic acid) microparticles prepared by a novel ultra-fine particle processing system and spray drying. Colloid Surface B Biointerface, 2015, 132:103-110.J Ji, J Zhang, J Chen, Y Wang, X Wang, N Dong, C Hu, H Chen, G Li, X Pan*, Wu C. Preparation and stabilization mechanism of emulsions stabilized by mixed sodium caseinate and soy protein isolate, Food Hydrocolloid, 2015, 51: 156-165. X Pan, K Han, X Peng, Z Yang, L Qin, C Zhu, C Wu*, Nanostructed cubosomes as advanced drug delivery system, Curr Pharm Design, 2013, (8): 6290-6297D Huang, L Wang, Y Dong, X Pan*, G Li, C Wu*, A novel technology using transscleral ultrasound to deliver protein loaded nanoparticles, Eur. J. Pharm. Biopharm. 2014,88:104-115.L Dian, Z Yang, F Li, Z Wang, X Pan*, X Peng, X Huang, Z Guo, G Quan, X Shi, B Chen, G Li, C Wu*, Cubic phase nanoparticles for sustained release of ibuprofen: formulation, characterization, and enhanced bioavailability study, Int. J. Nanomed. 2013,8: 845–854.W Wang#, Z Zhong#, Z Huang*, F Fu, W Wang, L Wu, Y Huang*, C Wu, X Pan*. Two different protein corona formation modes on Soluplus® nanomicelles. Colloid Surface B. 2022; 218:112744.W Wang#, Z Huang#, Y Huang#, X Zhang, J Huang, Y Cui, X Yue, C Ma, F Fu, W Wang, C Wu, X Pan*. Pulmonary delivery nanomedicines towards circumventing physiological barriers: Strategies and characterization approaches. Adv Drug Deliver Rev. 2022; 185: 114309.W Wang#, H Liu#, Z Huang*, F Fu, W Wang, L Wu, Y Huang*, C Wu, X Pan*. The effect of organic ligand modification on protein corona formation of nanoscale metal organic frameworks. Chinese Chem Lett. 2022; 33: 4185-4190.Z Huang#, F Fu#, L Wu#, W Wang, W Wang, C Shi, Y Huang*, X Pan*, C Wu. Bibliometric landscape of the researches on protein corona of nanoparticles. Front Mater Sci. 2021; 15: 477-493.W Wang, B Yang, Z Huang*, Y Huang, P Hu, X Pan*, C Wu. Investigating the effect of particle size on cellular uptake by aggregation-caused quenching probes encapsulated solid lipid nanoparticles, inhaled. J Pharm Innov. 2021.

授权专利:

吴传斌,吴涵,潘昕。水溶性药物无水反胶束纳米粒及其混悬型气雾剂的制备方法。ZL201310154231.3,授权公告日:20150506吴传斌,吉娟,潘昕。双蛋白共乳化体系及其制备方法和应用,ZL 201410513452.X,授权公告日:20160622潘昕,吴传斌,周焕彬,陈嘉树。益生菌微胶囊及其制备方法和应用,ZL 201510708165.9,授权公告日:20180406潘昕,黄莹,彭婷婷,张雪娟,表面纳米级粗糙结构的颗粒及其制备方法和应用。ZL 201610013832.6,授权公告日:2018.11.09潘昕,黄莹,梅丽玲,缓释立方液晶液体硬胶囊及其制备方法。ZL 201610013835.X,授权公告日:2018.12.11潘昕,郑腾羿,吴传斌。用于根管消毒的溶致液晶前体及其制备方法和应用,ZL 201610237606.6,授权公告日:2018.12.11潘昕,陈龙楷,冯地桑,黄莹,吴涵,吴传斌。磷脂蛋白质微粒复合微球及其制备方法,ZL 201610031750.4,授权公告日:2018.12.11吴传斌,谢业城,潘昕,黄莹,梅丽玲,陈航平,王倍,李娜。局部麻醉药的立方液晶原位凝胶注射剂及其制备方法,ZL 201611131813.X,授权公告日:2020.01.21吴传斌,牛博艺,吴巧利,权桂兰,潘昕。非诺贝特固体分散体及其制备方法和应用,ZL 201611200910.X,授权公告日:2020.01.14吴传斌,冯地桑,潘昕,权桂兰,黄莹,陈航平。固体分散体及其制备方法和应用,ZL 201611185254.0,授权公告日:2019.10.18吴传斌,张雪娟,赵紫玉,潘昕,黄莹,彭婷婷。多孔结构的载体颗粒及其制备方法和应用,ZL 201611124085.X,授权公告日:2019.09.20潘昕,彭婷婷,杨佩佩,朱春娥,吴传斌。石杉碱甲骨架微粒、口崩片及其制备方法,ZL201610944569.2,授权公告日:2019.04.19潘昕,梅丽玲,杨蓓蓓,吴传斌,黄莹,谢业城。液晶纳米粒前体微粒、自组装液晶纳米粒及其制备方法,ZL 201610887832.9,授权公告日:2019.06.18吴传斌,杨莉,李彦蓉,潘昕,黄莹,陈航平。马来酸噻吗洛尔立方液晶纳米粒滴眼液及其制备方法,ZL 201611227982.3,授权公告日:2019.09.20吴传斌,侯嫒琳,潘昕,权桂兰,黄莹,李露,陈航平。醋酸奥曲肽干粉吸入制剂及其制备方法,ZL 201611141634.4,授权公告日:2020.10.13吴传斌,赵紫玉,张雪娟,黄莹,潘昕。防潮抗湿的低密度载体颗粒及其制备方法和应用,中国专利号201611185899.4,授权公告日:2020.10.13吴传斌,湛正文,权桂兰,潘昕,陈航平。中空介孔二氧化硅纳米粒、纳米载体及其制备方法,中国专利号201611141631.0,授权公告日:2020.06.16吴传斌,王倍,张晓旭,潘昕,权桂兰,陈航平。三元基因传递系统的冻干制剂及其制备方法,中国专利号201611207547.4,授权公告日:2020.10.23李革,周焕彬,李顺怡,潘昕,朱春娥,陈航平。 耐酸、稳定的益生菌微胶囊及其制备方法和应用。中国:201611254327.7,授权公告日:2020.11.17吴传斌,梅丽玲,潘昕,黄莹,陈锦填,史旋,景卉。冬凌草甲素立方液晶纳米粒及其制备方法,中国专利号201611122471.5,授权公告日:2020.10.13吴传斌,林师麒,权桂兰,潘昕,蔡炳贞,侯嫒琳,杨佩佩。胸腺五肽可溶性微针及其制备方法,ZL 201710393418.7,授权公告日:2020.01.07吴传斌,李静,朱春娥,潘昕,杨莉,董妮。蛋白多肽类药物长效微球及其制备方法,ZL 201810522338.1,授权公告日:2020.09.29吴传斌,杨莉,朱春娥,龙婕妤,李静,潘昕,孙铭昊。共载盐酸阿霉素纳米粒和人参皂苷rh2的复合微球及其制备方法,ZL 201810474916.9,授权公告日:2020.09.08学术交流

大会报告:

1) Study on Delivering Macromolecule Drugs,The 1st Diwus Forum on Pharmaceutical Technology, Guangzhou, China, 10 April, 2017.

2) Influence of Polymers on the Dual Recrystallizations and Physicochemical Stability of Spray-dried Amorphous Solid Dispersion. 2016年中国药学大会, 中国北京。

3) 溶致液晶凝胶系统的研究及应用,2016中国药学大会,大会报告,2016年12月,中国北京。

4) The Design and Stabilized Peptide Drugs Used in Pressurized Metered Dose Inhalers(pMDI),2016中国药学大会,大会报告,2016年11月,中国南京。

5) 干粉吸入剂纳米粗糙载体的构建及其提高药物传递效率的机理研究,中国颗粒学会学术年会暨海峡两岸颗粒技术研讨会,大会报告,2016年8月,中国成都。

6) Dry Powder Inhaler Carrier with Nano-metered Topography Roughness Surface and its Enhancement of Lung Delivery Efficiency, Asian Graduate Congress   on Pharmaceutical Technology, July 9-13, 2016, Singapore.

7) Peptide drug formulation design based on pMDIs, 2015 SYSU-RMIT Joint Symposium, Nov 17-18,2015, Guangzhou China.

8) 蛋白质多肽气雾给药系统的设计与评价,第二届全国生物颗粒研讨会,大会报告,2015年12月,中国广州。

9) Spray-dried Mannitol-Chitosan as Blend Carrier for Dry Powder Inhalers, Particulate Processes in the Pharmaceutical Industry IV, Sep 11-14, 2014, Potsdam, Germany.

10) Ultra-fine Particle Process System and Its Application for the Drug-containing Microspheres, The 7th World Congress of Particle Technology, May 11-14, 2014, Beijing, China.

11) 临床营养十三五863重大项目立项前期论证会议,大会报告,2013年3月,中国北京。

12) 微丸片制剂产业化技术,中国颗粒学会第八届学术年会,分会场报告,2012年9月,中国杭州。

 

 

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